Crystal Mackall, M.D.
Pediatric Oncology Branch
Head, Immunology Section
Branch Chief
National Cancer Institute
Building 10 - Magnuson Clinical Center,
Room 1W-3750
10 Center Drive
Bethesda, MD 20892
Phone: 301-402-5940
Fax: 301-451-7010
cm35c@mail.nih.gov
Dr. Mackall is chief of the Pediatric Oncology Branch (POB) of the National Cancer Institute (NCI). She completed an accelerated 6-year B.S./M.D., program at the Northeastern Ohio Universities College of Medicine in 1984, followed by a combined internal medicine/pediatrics residency in 1988. She came to NCI in 1989 as a clinical associate in the POB, where she completed her clinical subspecialty training in 1992. She is board certified in internal medicine, pediatrics, and pediatric hematology/oncology. Dr. Mackall undertook postdoctoral scientific training in the Experimental Immunology Branch from 1990 to1996. Since that time, she has directed an independent research effort in the POB. Dr. Mackall has received international recognition for her work on T cell homeostasis and tumor immunology, and she leads an active translational research program that incorporates basic studies of immunology with clinical trials of immunotherapy for pediatric cancer. She has received numerous awards, including the NIH Distinguished Clinical Teacher Award in 2000, an NCI Mentor of Merit Award in 2003, and the NCI Director's Award in 2003. She has authored more than 100 scientific publications and is a member of the American Society of Clinical Investigation. She was appointed acting chief of the POB in 2005 and chief of the POB in 2008.
Dr. Mackall's Clinical Trial(s):
NCI’s Center for Cancer Research (CCR) is currently conducting the following trial(s) for patients with pediatric solid tumors. Click on the trial(s) below for additional details, including a summary of key eligibility criteria, study outline, and information on how to contact the study team directly.
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CC Grand Rounds: (1) Exploring the Long-Term Outcome of Allogeneic Stem Cell Tranplantation (2) Bench-to-Bedside: From T Cell Homeostasis to Immunotherapy for Cancer Speaker(s): John Barrett, M.D., Chief, Allogeneic Stem Cell Transplantation Section, Hematology Branch, NHLBI June 16, 2010 60 minutes http://videocast.nih.gov/launch.asp?15966 |
Some of the resources above require the use of a standalone player: Download Free RealPlayer 
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Clinical Trials Research
The goal of the Immunology Section of the Pediatric Oncology Branch is to develop effective immune based therapies for pediatric cancer. Guided by a bench-to-bedside-to-bench approach to research, we build upon expertise in the biology of T cell homeostasis to develop new therapies that enhance immune responses to tumor associated antigens following T cell depleting chemotherapy and can amplify antitumor immune responses in hosts without T cell depletion.
Read more
 | Pediatric Oncology Branch Web Site |
 | Watch/Listen to Dr. Mackall's videocast/podcast |
